Akki's Lab - Publications

2024

Nabendu Murmu, Paramita Ghosh, Akhileshwar Namani, Tapas Patra. Glyoxylate supplementation ameliorates colitis-associated colon cancer progression. Journal of Cellular Physiology (2024), 2024 Sep 5:e31394. doi: 10.1002/jcp.31394. (IF-2023: 4.5). [Article link]
Sri Vidya Ramisetti, Tapas Patra, Vinayak Munirathnam, Jyothi Venkat Sainath, Durgadevi Veeraiyan, Akhileshwar Namani. NRF2 Signaling Pathway in Chemo/Radio/Immuno-Therapy Resistance of Lung Cancer: Looking Beyond the Tip of the Iceberg.Archivos de Bronconeumologia(2024), doi: 10.1016/j.arbres.2024.06.021. (Corresponding author) (IF- 2023: 8.7). [Article link]
Akhileshwar Namani, Durga Devi Veeraiyan, Tapas Patra, A comparative analysis indicates SLC7A11 expression regulate the prognostic value of KEAP1-NFE2L2-CUL3 mutations in human Uterine Corpus Endometrial Carcinoma, Free Radical Biology and Medicine, 2024 Jun 13;222:223- 228. doi: 10.1016/j.freeradbiomed.2024.06.008 (First author) (IF-2023: 7.1). [Article link]

Qinqin Cui, Wei Wang, Akhileshwar Namani*, Hongyan Wang, Ahmed Hammad, Pu Huang, Yang Gao, Mohamed Elshaer, Yihe Wu, Xiu Jun Wang, Xiuwen Tang. NRF2 has a splicing regulatory function involving the survival of motor neuron (SMN) in non-small cell lung cancer. Oncogene 42, 2751–2763 (2023). doi: 10.1038/s41388-023-02799-z (*Equal contribution) (IF-2023: 6.9). [Article link]

Ahmed Hammad, Zhao-Hong Zheng, Akhileshwar Namani, Mohamed Elshaer, Xiu Jun Wang, Xiuwen Tang. Transcriptome analysis of potential candidate genes and molecular pathways in colitis-associated colorectal cancer of Mkp-1-deficient mice.BMC Cancer 2021 (1), 1-13. DOI: 10.1186/s12885-021-08200-0. (IF-2023: 3.4). [Article link]

Mohamed Elshaer, Ahmed Islam ElManawy, Ahmed Hammad, Akhileshwar Namani, Xiu Jun Wang, Xiuwen Tang. (2020). Integrated data analysis reveals significant associations of KEAP1 mutations with DNA methylation alterations in lung adenocarcinomas.Aging 03/2020;12. DOI: 10.18632/aging.103068 (IF-2023: 3.9) [Article link]
Jingwen Zhang, Huiling Cui, Akhileshwar Namani*, Jun Yao, Hong Deng, Xiuwen Tang, Xiu Jun Wang. (2020). Transcriptomic profiling identifies a critical role of Nrf2 in regulating the inflammatory response to fly ash particles in mouse lung. Ecotoxicology and Environmental Safety 01/2020; 190:110132. DOI: 10.1016/j.ecoenv.2019.110132 (*Equal contribution) (IF-2023: 6.2). [Article link]
Jingwen Zhang, Yiping Chen, Akhileshwar Namani*, Mohamed Elshaer, Zhinong Jiang, Hongfei Shi, Xiuwen Tang, Xiu Jun Wang. (2020). Comparative transcriptome analysis reveals Dusp1 as a critical regulator of inflammatory response to fly ash particle exposure in mouse.Ecotoxicology and Environmental Safety 01/2020; 190:110116. DOI: 10.1016/j.ecoenv.2019.110116 (*Equal contribution) (IF-2023: 6.2). [Article link]

Ahmed Hammad, Zhao-Hong Zheng, Yang Gao,Akhileshwar Namani, Hong-Fei Shi, Xiuwen Tang. Identification of novel Nrf2 target genes as prognostic biomarkers in colitis-associated colorectal cancer in Nrf2-deficient mice.Life Sciences 10/2019; 238:116968. DOI: 10.1016/j.lfs.2019.116968. (IF-2023: 5.2). [Article link]
Akhileshwar Namani, Kaihua Liu, Shengcun Wang, Xihang Zhou, Yijiao Liao, Hongyan Wang, Xiu Jun Wang, Xiuwen Tang. (2019). Genome-wide global identification of NRF2 binding sites in A549 nonsmall cell lung cancer cells by ChIP-Seq reveals NRF2 regulation of genes involved in focal adhesion pathways.Aging 12/2019; 11. DOI:10.18632/aging.102590 (IF-2023: 3.9).[Article link]
Ahmed Hammad, Akhileshwar Namani, Mohamed Elshaer, Xiu Jun Wang, Xiuwen Tang. (2019). NRF2 Addiction in Lung Cancer Cells and Its Impact on Cancer Therapy.Cancer Letters 09/2019; DOI: 10.1016/j.canlet.2019.09.016. (IF-2023: 9.1). [Article link]
Akhileshwar Namani, Zhaohong Zheng, Xiu Jun Wang, Xiuwen Tang. (2019). Systematic Identification of Multi-Omics-based Biomarkers in KEAP1 Mutated TCGA Lung Adenocarcinoma.Journal of Cancer 01/2019; 10(27):6813-6821., DOI:10.7150/jca.35489. (IF-2023: 3.3). [Article link]

Akhileshwar Namani, Md. Matiur Rahaman, Ming Chen, Xiuwen Tang. Gene-expression signature regulated by the KEAP1-NRF2-CUL3 axis is associated with a poor prognosis in head and neck squamous cell cancer. BMC Cancer 12/2018; 18(1). DOI: 10.1186/s12885- 017-3907-z. (IF-2023:3.4) [Article link]
Jing Li, Hongyan Wang, Zhaohong Zheng, Lin Luo, Peng Wang, Kaihua Liu, Akhileshwar Namani, Zhinong Jiang, Xiu Jun Wang, Xiuwen Tang. (2018). Mkp-1 Cross-talks With Nrf2/Ho-1 Pathway Protecting Against Intestinal Inflammation.Free Radical Biology and Medicine 07/2018; 124.DOI: 10.1016/j.freeradbiomed.2018.07.002. (IF-2023: 7.1). [Article link]

Akhileshwar Namani, Jing Li, Xiu Jun Wang, Xiuwen Tang. (2017). A Review of Compounds for Prevention of Colorectal Cancer. Current Pharmacology Reports 08/2017; 3(5):1-11. DOI: 10.1007/s40495-017-0101-6. (Invited review). [Article link]
Akhileshwar Namani, Qin Qin Cui, Yihe Wu, Hongyan Wang, Xiu Jun Wang, Xiuwen Tang. (2017). NRF2-regulated metabolic gene signature as a prognostic biomarker in non-small cell lung cancer.Oncotarget 07/2017; 8(41). DOI:10.18632/oncotarget.19349. (IF-2016: 5.168). [Article link]

Syed Minhaj Uddin Ahmed, Lin Luo, Akhileshwar Namani, Xiu Jun Wang, Xiuwen Tang.(2016). Nrf2 Signaling Pathway: Pivotal Roles in Inflammation.Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 11/2016; 1863(2). DOI: 10.1016/j.bbadis.2016.11.005. (IF-2023: 4.2). [Article link]

Akhileshwar Namani, Yulong Li, Xiu Jun Wang, Xiuwen Tang. (2014). Modulation of NRF2 signaling pathway by nuclear receptors: Implications for cancer.Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 05/2014; 1843(9). DOI: 10.1016/j.bbamcr.2014.05.003. (IF-2023: 4.6). [Article link]
Mingjun Xiang, Akhileshwar Namani, Shijun Wu, Xiaoli Wang. (2014). Nrf2: Bane or blessing in cancer? Journal of Cancer Research and Clinical Oncology 03/2014; 140(8). DOI: 10.1007/s00432-014- 1627-1. (IF-2023: 2.7). [Article link]